PATHOGENTIC TRIAL ( DRUG PROVING ) OF HOUSE DUST ALLERGEN


Grading


1st grade- Bold and underlined- More than 3 provers

2nd grade- Bold and Italic – Seen in at least 2 provers

3rd grade- Plain text- Seen in single provers



The drug picture that evolved is as follows:
Mind:
Dullness, lack of interest in studies ,
Lack of concentration.
Indolence
Wants to be quiet
Irritability


Feels very lonely with weeping. Quiet and reserved.
Indifference

Depression
Lack of confidence

Anger from contradiction, shouting when angry
Remorseful in the morning
Restlessness, wants to move about.
Disturbing thoughts

Head:
Pain in occipital region < ascending > after sleep
Pain in temporal region
Headache in the morning < reading, < noise,< exertion > after sleep
Heaviness of head R side< bending forwards < evening.
Headache with nausea < 6-8 pm
External: Itching of scalp < night, scratching

Face
Eruptions on forehead with itching,
Pustular eruptions
Eruptions reddish
Painful eruptions

Nose:
Watery discharge < sun exposure to, <chalk, < dust, < traveling < damp air > dry air.
Obstructed nose has to breathe through mouth. < waking > moving about
Sneezing at change of temp (cold to warm room).< morning 9 -10 am,<evening 6 -8pm
Painful pustules on nostril.
Itching sensation in the nose with sneezing and irritation in throat.

Eyes:
Watering from eyes along with sneezing.
Itching and eruptions on margin of eye lids < rt. side, traveling
Swelling of upper lids, with sensation of heaviness

Ear:
Mild pain and itching in left ear lasting for few minutes. Painful boil behind ear (Rt)

 

Mouth:
Feeling of dryness increased with thirst
Salivation with thirst for cold water. Moist mouth but, wants to take sips of water to relieve dryness ( ½ glass at a time)
Apthae on tongue, left side margin, inside lower lip, stitching pain, , burning and pricking sensation< spicy food. White coated tongue. Water tastes sweet.

Throat:
Dryness of throat > warm drinks
Hoarseness of voice < talking , < cold water .
< evening
Rawness of throat with pain < swallowing (empty) and food

< morning, <evening around 4pm. < coughing, < sneezing.
Irritation posterior wall of pharynx < cold drinks < morning, < evening
> night after dinner
Tendency to hawk and hem, wants to clear throat.
Throat red with white spots on tonsils, granulation posterior wall of pharynx.

Stomach:
Appetite increased < morning
and < evening.

Craving for spicy sour food

Thirst increased for frequent sips of water
Nausea after breakfast, night < lying down, < after eating > sitting up.
Thirst decreased
Sinking sensation
Hungry empty feeling.
Eructations after meals

Fullness after eating little

Abdomen:
Flatulence, passing of offensive flatus
< evening > passing flatus, eructations temporarily relieve
Pain abdomen > motion, moving about
Pain in both hypochondrium < sitting > motion or moving about

Stool:
Painless loose stools,
Constipation with no urge for stool

stools gushing with mucus, pain in umbilical region after stool lasting for 1-2 hrs,
stools clay coloured, unsatisfactory

Urine :

Offensiveness
< before menses > after menses,
Frequency of urine increased

Male:
Increased sexual desire,
Thoughts sexual with frequent erections followed by masturbation.

Sexual desire diminished, incomplete erections, night emissions, relaxed genitals.

Female:
Cramp like pains felt in the lower abdomen one day before menses and the first of day of the periods, Menses early,scanty

Respiratory :
Rawness of throat extends downwards to larynx and chest.
Cough from irritation in throat.

Breathing increased with feeling of cold air being taken in.
Pain in L upper chest lasting for few minutes.
Cough < evening with itching in the throat> warm drinks
Cough with easy expectoration of light grey mucus

Chest:
Sharp pinching pain in left nipple lasting for few seconds

Back:
Pain lower back, (lumbo-sacral) > rest or sleep

Itching eruptions on back

Extremities:
Pain in thighs, (Right to left) with stiffness.
Pain in knee joints with weakness in limbs
Pain in upper arms. with weakness and trembling while holding objects.
Roughness of skin of palms with peeling,
Itching on arms, tiny eruptions appearing after scratching.
Itching on fingers < night, <warmth, burning after itching > cold application,
Eruption on thigh
Pain in leg extending from hip to ankle

Skin: Eruption on back of neck, chest, crop of pimples on back. Very tiny in size < Rt side
Eruption as have we seen in different parts of the body.

Fever: Feeling of chilliness with desire to cover, general weakness
No fever as such, weakness associated with and sleepiness. Wants to lie down.

Perspiration: Sweat on forehead after sneezing.

Sleep: Unrefreshed in the morning . Drowsiness
Difficulty getting up in the morning.

Sleeplessness at night, sleep not sound
Dreams of eating mud tasting like chocolate.

Modalities: < evening, < morning, < exertion, < exposure to dust
> rest, > sleep
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